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When Perkinsus is found, determining which species is present requires specialized molecular testing that few labs are able to do. Because of the potential importance of these organisms in shellfish disease, it is strongly recommended that an expert in shellfish diseases be consulted when Perkinsus is found or suspected. Of the Perkinsus species, P. This document primarily addresses these two species. Table 1 lists the known species of Perkinsus, the known hosts, geographical location where they have been found, and reportability. Signs of Perkinsus infection in molluscs Clinical signs of disease in Sitecom CN-129 molluscs are non-specific.

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Infected animals may gape, have a pale digestive gland, lose Sitecom CN-129 condition, demonstrate mantle retraction, and contain white nodules in various tissues. Or, they may be found dead. Infection with either P. The recent northward Sitecom CN-129 extension of P. Perkinsus marinus causes disease and mortality in the Eastern oyster Crassostrea virginica, a commonly cultured and wild-harvested food species.

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The presence of this parasite can damage Sitecom CN-129 fisheries and severely limits commercial production of the Eastern oyster. The Pacific Sitecom CN-129 C. The hard clam Mercenaria mercenaria, another commonly cultured species, is not susceptible to infection with P. However, if hard clams are located near infected oysters, they may ingest P. Subsequent movement of these clams may introduce a different strain of P.


Perkinsus olseni Perkinsus olseni is a protistan parasite of many molluscs and was first identified in several species of the gastropod abalone Haliotis along the coast of Australia. Venerid clams Sitecom CN-129 particularly susceptible to infection with P.

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Venerid clams are found around the world and include species such as the hard clam Mercenaria mercenaria, and the Manila clam Venerupis philippinarum. To date, it has not been shown to cause disease in the hard Sitecom CN-129 M. Perkinsus Infections of Bivalve Molluscs Other Perkinsus species of North American bivalves The soft shell clam Mya arenaria and Baltic clam Macoma balthica, found in Virginia and Maryland, are Sitecom CN-129 to infection with Perkinsus chesapeaki, and a Perkinsus species has been identified in the hard clam M.

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These two species of Perkinsus rarely cause severe disease or kill their host bivalves. The life cycle of Perkinsus species All Perkinsus species have a similar life cycle consisting of multiple stages, all of which cause tissue damage in the mollusc and are infective. The first Sitecom CN-129 is Sitecom CN-129 zoospore.

The zoospore is motile, which means that it can swim freely in the water by moving its two flagella. The host ingests the zoospore, which then becomes Sitecom CN-129 trophozoite.

The non-motile trophozoite multiplies in a vegetative form Sitecom CN-129 the host tissue. Perkinsus marinus primarily infects hemocytes the blood cells of the mollusc.

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In the infected tissue, trophozoites develop Sitecom CN-129 large vacuole and a displaced nucleus. The infected cell is similar in appearance to a signet ring, and is called a signet ring cell.


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